As of May 2026, Melissa De Sousa is best known for Criminal Minds and Shameless. Find every show and movie Melissa De Sousa has starred in — and where to watch them — below.
Melissa De Sousa

Melissa De Sousa

Actress Born 1967 New York City, New York, USA 12 TV Shows 8 Movies

Melissa De Sousa is an actress best known for her role as Shelby in the 1999 romantic comedy-drama film The Best Man, its 2013 sequel The Best Man Holiday, Gabriella Jimenez in BET's Reed Between the Lines, and Ana Lopez in Black Lightning.

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📺 Melissa De Sousa's TV Shows

Criminal Minds
Adele McCord
2005
Shameless
Tina
2011
Castle
Liz Penn
2009
The Kelly Clarkson Show
Self
2019
ER
Estella
1994
Elementary
Luz Horowitz
2012
Ghost Whisperer
Christine Nelson
2005
Black Lightning
Chief Ana Lopez
2018
Moesha
Jennifer
1996
Bel-Air
Steph
2022
One on One
Natalie
2001
Living Single
Carmen
1993

🎬 Melissa De Sousa's Movies

Miss Congeniality
Karen Krantz
2000
The Ron Clark Story
Marissa Vega
2006
Laurel Canyon
Claudia
2003
The Best Man Holiday
Shelby
2013
Lockdown
Krista
2000
The Best Man
Shelby
1999
Ride
Leta
1998
Bats: Human Harvest
O'Neal
2007

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