Melissa Ponzio

Actress Born 1972 New York City, New York, USA 8 TV Shows 8 Movies

Melissa Ponzio is an actress from New York City, New York, USA, born in 1972. Best known for Chicago Fire, The Walking Dead, One Tree Hill. Melissa Ponzio has 25 television credits and 17 film credits.

Melissa Ponzio's screen work to date leans strongly toward Drama and Comedy, a consistent thread across her credits so far.

Melissa Ponzio's most notable role to date came in The Walking Dead (2010), where she played Karen. She also appeared in Teen Wolf (2011) as Melissa McCall. Most recently appeared in Weapons (2025) as Archer's Wife.

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