As of July 2026, Grey's Anatomy Season 4 aired in 2007 with 17 episodes — streaming now on Disney Plus. Full episode guide and where to watch below.
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Grey's Anatomy Season 4

2007 17 Episodes Drama ⭐ 8/10

Right now you can watch Grey's Anatomy Season 4 on and — and it holds up to as much attention as you give it. A single, tightly-focused season means there is plenty to get through without ever feeling padded. Its 8/10 TMDB score, built from 10,965 ratings, reflects a title that consistently delivers. Ellen Pompeo anchors it with a performance that rewards close attention. Available now — press play and find out why people keep recommending it.

Grey's Anatomy Season 4 is not trying to be everything to everyone, and that focus is exactly what makes it work. Grey's Anatomy Season 4 takes its time building the world its characters inhabit, and the patience pays off. Enter a world of change in the irresistible and unforgettable fourth season of Grey's Anatomy. Love, lies, and family ties are revealed as the surgeons of Seattle Grace discover that their choices have major unintended consequences. And coupled with the arrival of some very eager new interns, life at the hospital sizzles with more emotion, excitement, and heartbreak than ever before. Ellen Pompeo and Chandra Wilson lead a cast that brings real weight to the material. It was aired in 2007. What elevates Grey's Anatomy Season 4 is a refusal to let any character off the hook too easily. The consistency throughout is what elevates it — not every moment is the best, but none of them are a reason to stop watching.

Viewers drawn to character-driven storytelling will find plenty to sit with in Grey's Anatomy Season 4. It stands on its own even without an obvious comparison point. Short enough to finish in a weekend, substantial enough to feel satisfying. Ellen Pompeo anchors a cast that never overplays its hand. The kind of drama that stays with you well after the finale.

📡 Where to Watch Grey's Anatomy Season 4

🇦🇺 Australia
🇺🇸 United States
🇬🇧 United Kingdom
🇨🇦 Canada
🇳🇿 New Zealand
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🎬 Grey's Anatomy Season 4 — Episode Guide

E1
A Change Is Gonna Come
2007-09-27
Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Another two new interns will ...
E2
Love/Addiction
2007-10-04
A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Alex investigates the cause of the incident by talking to a really old guy who lived in the building. Jane Burke shows up t...
E3
Let the Truth Sting
2007-10-11
The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unless Mark and Richard can perform a radical new surgery. George impresses the other interns at work but at home he is tryi...
E4
The Heart of the Matter
2007-10-18
A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery for an injury he sustained while playing the game. Another patient's, named Courtney, finds out that her cancer is back.
E5
Haunt You Every Day
2007-10-25
It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what most of the doctors believe is an unnecessary surgery. One of the patients is in the hospital because they tried to carve ...
E6
Kung Fu Fighting
2007-11-01
A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them convinces an intern to take their place.
E7
Physical Attraction, Chemical Reaction
2007-11-08
Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith can barely handle it with Lexie anymore.
E8
Forever Young
2007-11-15
There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her at the hospital.
E9
Crash Into Me (1)
2007-11-22
An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.
E10
Crash Into Me (2)
2007-12-06
Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles to balance her personal life with her work.
E11
Lay Your Hands on Me
2008-01-10
George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in her. Alex treats a faith healer.
E12
Where The Wild Things Are
2008-04-24
Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of her current off-again ex-boyfriend. The doctor's are in the midst of a competition.
E13
Piece of My Heart
2008-05-01
Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.
E14
The Becoming
2008-05-08
The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affected by Burke's career developments.
E15
Losing My Mind
2008-05-15
Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Christina continues to act strangely.
E16
Freedom (1)
2008-05-22
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
E17
Freedom (2)
2008-05-22
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

🎭 Cast of Grey's Anatomy Season 4

Ellen Pompeo
Ellen Pompeo
Meredith Grey
Chandra Wilson
Chandra Wilson
Miranda Bailey
Sandra Oh
Sandra Oh
Cristina Yang
Justin Chambers
Justin Chambers
Alex Karev
James Pickens Jr.
James Pickens Jr.
Richard Webber
Patrick Dempsey
Patrick Dempsey
Derek Shepherd
Katherine Heigl
Katherine Heigl
Izzie Stevens
Sara Ramirez
Sara Ramirez
Callie Torres
Eric Dane
Eric Dane
Mark Sloan
Chyler Leigh
Chyler Leigh
Lexie Grey

📋 All Seasons of Grey's Anatomy

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