As of July 2026, Samantha Who? Season 1 aired in 2007 with 15 episodes — streaming now on Disney Plus. Full episode guide and where to watch below.
Samantha Who? Season 1 poster
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Samantha Who? Season 1

2007 15 Episodes Comedy ⭐ 7/10

Right now you can watch Samantha Who? Season 1 on — and it is funnier than its reputation suggests. The show says what it needs to say in a single season, no filler. With 79 viewer ratings on TMDB, this is not a title flying under the radar. Christina Applegate is the obvious draw, but the whole ensemble earns its laughs. Available now — press play and find out why people keep recommending it.

There is a reason Samantha Who? Season 1 keeps coming up in conversation. Samantha Who? Season 1 gets the fundamentals right first, then finds room to get weird with it. Season 1 of Samantha Who? Includes 15 episodes. It aired from October 2007 to May 2008. Christina Applegate and Jennifer Esposito lead a cast that brings real weight to the material. It was aired in 2007. The real test of any comedy is whether it is still funny once you know all the jokes, and Samantha Who? Season 1 holds up on rewatch in a way that separates it from one-off curiosities. It knows exactly what it is, and does not try to be anything else.

If you need a comedy that actually makes you laugh, Samantha Who? Season 1 is a strong candidate. It has built its own audience without needing a direct comparison. A contained run means every episode is doing real work. Christina Applegate is funny in a way that holds up on rewatch. Put it on when you need something guaranteed to land.

📡 Where to Watch Samantha Who? Season 1

🇦🇺 Australia
🇨🇦 Canada
🇳🇿 New Zealand
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🎬 Samantha Who? Season 1 — Episode Guide

E1
Pilot
2007-10-15
Wretched with amnesia after an accident, Samantha attempts to discover her life again. After being the victim of a hit and run, Sam awakens to the shock of everyone that she doesn't remember any of them, not even her parents who were standing over her bedside.
E2
The Job
2007-10-22
It's Samantha's first day back to work and her first board meeting gives her a shocking look at just how cutthroat and competitive she really was.
E3
The Wedding
2007-10-29
Sam attends the wedding of one of her so called friends, only to realize that she forgot that she had been uninvited by the bride earlier.
E4
The Virgin
2007-11-05
Since Samantha has no memories of the past, including her sexual experiences, she is faced with the decision of waiting this time for the right guy to come along, or to experiment.
E5
The Restraining Order
2007-11-12
Sam learns that one of her ex-boyfriends has a restraining order out against her, while she is on a walk with Todd. She then wonders if her poor relationship with her father is the cause of her need for constant attention.
E6
The Hypnotherapist
2007-11-19
As a last ditch effort to try and regain some of her lost memory, Sam seeks professional help from a hypnotherapist, but doesn't get the help she expected. Sam hears a bombshell confession from Todd.
E7
The Hockey Date
2007-11-26
Regina sets Samantha up on a blind date with the man who is refinishing her floors. She turns to Todd for advice when she leads the guy to think she is an avid hockey fan.
E8
The Car
2007-12-03
Sam gets her father's car into an accident and pushes it into a lake, making him think it was stolen. He feels so bad for her that he ends up buying her a new car. Regina discovers clues about the accident and uses that as blackmail to force Sam to model at a party.
E9
The Break-Up
2007-12-10
Sam thinks she's in love with Kevin and steps things up a bit, but it may prove to be more than Kevin can handle.
E10
The Girlfriend
2008-04-07
Sam is forced to move back in with Todd and his new girlfriend, Chloe, after she finds out she could face an eviction because she sublet her apartment to Todd. Regina and Dena bond when Sam misses a makeover night.
E11
The Boss
2008-04-14
The guy that Andrea has a thing for, asks Samantha to marry him. He also turns out to be the wealthy owner of the real estate firm that they both work at. Samantha worries that it may harm their friendship more than anything else.
E12
The Butterflies
2008-04-21
Samantha finds out about an endangered butterfly habitat and needs to stop her boss and the firm's construction project that would kill them. She decides to use Dena, who is clueless about Sam's plan, to go out with her boss and persuade him to stop the construction project. After Todd and Sam's pas...
E13
The Gallery Show
2008-04-28
Sam is going to Todd's photo exhibit, but doesn't want to go alone, so she asks Craig, whom she thinks is a complete stranger, to join her. Sam soon gets the hint that they've met before and things doing go smoothly. Kevin discovers a demeaning picture of Sam in Todd's photo collection.
E14
The Affair
2008-05-05
Samantha is suspicious about Regina's action, which lead her to believe she is having an affair. But she's not alone. Todd is cheating on Chloe, who is none the wiser, with Samantha. Dena and Regina are contemplating opening up their own coffee shop.
E15
The Birthday
2008-05-12
In the season finale, Samantha is beginning to think that Chloe is using the sympathy card by saying her aunt is sick, just so Todd won't break up with her like he promised Samantha. Andrea and Regina are having several disagreements over how to plan Samantha's birthday party.

🎭 Cast of Samantha Who? Season 1

Christina Applegate
Christina Applegate
Samantha Newly
Jennifer Esposito
Jennifer Esposito
Andrea Belladonna
Kevin Dunn
Kevin Dunn
Howard
Melissa McCarthy
Melissa McCarthy
Dena
Tim Russ
Tim Russ
Frank
Barry Watson
Barry Watson
Todd
Jean Smart
Jean Smart
Regina Newly

📋 All Seasons of Samantha Who?

Season 2

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